3DTG
Structural analysis of mycobacterial branched chain aminotransferase- implications for inhibitor design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Branched-chain amino acid aminotransferase | polymer | 372 | 40366.2 | 2 | UniProt (A0R066) Pfam (PF01063) | Mycobacterium smegmatis | |
| 2 | C, F (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D (A) | O-benzylhydroxylamine | non-polymer | 123.2 | 1 | Chemie (OBZ) | |||
| 4 | E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 368 (UniProt: A0R066)
| PDB | External Database | Details |
|---|---|---|
| Ala -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80732.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 801.6 | |
| All* | Total formula weight | 81534.1 |
