3DRM

2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-1-antitrypsin	polymer	404	45657.8	1	UniProt (P01009) Pfam (PF00079) In PDB	Homo sapiens (human)	Alpha-1 protease inhibitor, Alpha-1-antiproteinase
2		water	water		18.0	164	Chemie (HOH)

Sequence modifications

A: 2 - 394 (UniProt: P01009)

PDB	External Database	Details
Met -9	-	expression tag
Arg -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Thr 1	-	expression tag
Phe 114	Thr 138	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45657.8
All*	Total formula weight	45657.8

*Water molecules are not included.