3DPE
Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Neutrophil collagenase | polymer | 163 | 18111.7 | 1 | UniProt (P22894) Pfam (PF00413) In PDB | Homo sapiens (Human) | Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL |
| 2 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A | N-{[2-(2-amino-3,4-dioxocyclobut-1-en-1-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]methyl}-4-oxo-3,5,6,8-tetrahydro-4H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidine-2-carboxamide 7,7-dioxide | non-polymer | 539.6 | 1 | Chemie (AXB) | |||
| 5 | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18111.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 750.6 | |
| All* | Total formula weight | 18862.3 |
