3DOL
Crystal structure of L100I mutant HIV-1 reverse transcriptase in complex with GW695634.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Reverse transcriptase/ribonuclease H | polymer | 560 | 64594.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus type 1 (HIV-1) | p66 RT |
| 2 | B (B) | p66 RT | polymer | 440 | 51399.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus type 1 (HIV-1) | |
| 3 | C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E (A) | N-({4-[({4-chloro-2-[(3-chloro-5-cyanophenyl)carbonyl]phenoxy}acetyl)amino]-3-methylphenyl}sulfonyl)propanamide | non-polymer | 574.4 | 1 | Chemie (GWI) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Ile 100 | Leu 687 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115994.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 764.4 | |
| All* | Total formula weight | 116758.4 |
