3DNG
Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neutrophil collagenase | polymer | 163 | 18111.7 | 2 | UniProt (P22894) Pfam (PF00413) | Homo sapiens (Human) | Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL |
| 2 | C, D, H, I (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | E, F, J, K (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | G, L (A, B) | (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide | non-polymer | 467.5 | 2 | Chemie (AXA) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36223.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1356.9 | |
| All* | Total formula weight | 37580.4 |
