3DM2
Crystal structure of HIV-1 K103N mutant reverse transcriptase in complex with GW564511.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Reverse transcriptase/ribonuclease H | polymer | 560 | 64579.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) UniProt (by SIFTS) (A7YKL0) In PDB | Human immunodeficiency virus type 1 (HIV-1) | p66 RT |
| 2 | B | p51 RT | polymer | 440 | 51384.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (Q74596) In PDB | Human immunodeficiency virus type 1 (HIV-1) | |
| 3 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | A | N-{4-[amino(dihydroxy)-lambda~4~-sulfanyl]-2-methylphenyl}-2-(4-chloro-2-{[3-fluoro-5-(trifluoromethyl)phenyl]carbonyl}phenoxy)acetamide | non-polymer | 546.9 | 1 | Chemie (GWE) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 690 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 690 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115963.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 736.9 | |
| All* | Total formula weight | 116700.7 |
