3DLZ
Crystal structure of human haspin in complex with AMP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase haspin | polymer | 357 | 40711.5 | 1 | UniProt (Q8TF76) Pfam (PF12330) In PDB | Homo sapiens | Haploid germ cell-specific nuclear protein kinase, H-haspin, Germ cell-specific gene 2 protein |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
5 | water | water | 18.0 | 462 | Chemie (HOH) |
Sequence modifications
A: 465 - 798 (UniProt: Q8TF76)
PDB | External Database | Details |
---|---|---|
Met 442 | - | expression tag |
His 443 | - | expression tag |
His 444 | - | expression tag |
His 445 | - | expression tag |
His 446 | - | expression tag |
His 447 | - | expression tag |
His 448 | - | expression tag |
Ser 449 | - | expression tag |
Ser 450 | - | expression tag |
Gly 451 | - | expression tag |
Val 452 | - | expression tag |
Asp 453 | - | expression tag |
Leu 454 | - | expression tag |
Gly 455 | - | expression tag |
Thr 456 | - | expression tag |
Glu 457 | - | expression tag |
Asn 458 | - | expression tag |
Leu 459 | - | expression tag |
Tyr 460 | - | expression tag |
Phe 461 | - | expression tag |
Gln 462 | - | expression tag |
Ser 463 | - | expression tag |
Met 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40711.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 495.7 | |
All* | Total formula weight | 41207.1 |