3DLQ
Crystal structure of the IL-22/IL-22R1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | I | Interleukin-22 | polymer | 151 | 17123.7 | 1 | UniProt (Q9GZX6) Pfam (PF14565) In PDB | Homo sapiens (Human) | IL-22, IL-10-related T-cell-derived-inducible factor, IL-TIF |
| 2 | R | Interleukin-22 receptor subunit alpha-1 | polymer | 211 | 24154.4 | 1 | UniProt (Q8N6P7) Pfam (PF01108) In PDB | Homo sapiens (Human) | IL-22R-alpha-1, Cytokine receptor family 2 member 9, CRF2-9 |
| 3 | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
I: 29 - 179 (UniProt: Q9GZX6)
R: 18 - 228 (UniProt: Q8N6P7)
| PDB | External Database | Details |
|---|---|---|
| Ala 40 | Cys 40 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Leu 204 | Cys 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41278.0 | |
| All* | Total formula weight | 41278.0 |
