3DL9
Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P450 2R1 | polymer | 479 | 55141.3 | 2 | UniProt (Q6VVX0) Pfam (PF00067) | Homo sapiens | Vitamin D 25-hydroxylase |
| 2 | C, D (C, D) | Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | branched | 1153.0 | 2 | In PDB BIRD (PRD_900012) GlyTouCan (G01435GL) | beta-cyclodextrin | ||
| 3 | E, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | F, H (A, B) | (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol | non-polymer | 412.6 | 2 | Chemie (V2H) PubChem (20839094) PubChem (21767860) PubChem (21767861) PubChem (177513624) PubChem (24779618) PubChem (44144476) PubChem (44593765) PubChem (46705423) PubChem (46931009) PubChem (53882687) PubChem (53882688) PubChem (53882689) PubChem (56962490) PubChem (59043370) PubChem (60008942) PubChem (441413) PubChem (73946279) PubChem (59904416) PubChem (87091395) PubChem (87607620) PubChem (87607621) PubChem (88021956) PubChem (88545507) PubChem (88595738) PubChem (89667121) PubChem (89667123) PubChem (89808991) PubChem (89808992) PubChem (90820058) PubChem (90883326) PubChem (71311851) PubChem (73707407) PubChem (87404216) PubChem (88552385) PubChem (91280042) PubChem (91505253) PubChem (4479094) PubChem (91885478) PubChem (91999651) PubChem (5281107) PubChem (98115805) PubChem (6850801) PubChem (6122659) PubChem (9801809) PubChem (126843107) PubChem (6384236) PubChem (96844301) PubChem (98115804) PubChem (98115806) PubChem (98115807) PubChem (9547235) PubChem (9801807) PubChem (9801808) PubChem (121595948) PubChem (9953511) PubChem (123893246) PubChem (124005144) PubChem (124225394) PubChem (124225395) PubChem (124225396) PubChem (124428600) PubChem (11546083) PubChem (11553381) PubChem (11742432) PubChem (124527073) PubChem (124527517) PubChem (124527518) PubChem (12051245) PubChem (13080219) PubChem (13080220) PubChem (125418919) PubChem (125418932) PubChem (125418939) PubChem (129009893) PubChem (129010344) PubChem (174238576) PubChem (129317879) PubChem (129606947) PubChem (129606948) PubChem (129629162) PubChem (131674059) PubChem (134692387) PubChem (134694726) PubChem (134814113) PubChem (134814136) PubChem (154790159) PubChem (155293227) PubChem (162342629) PubChem (162489852) PubChem (168322470) PubChem (171149019) PubChem (171381871) PubChem (172878429) PubChem (172897949) PubChem (173519237) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B: 32 - 501 (UniProt: Q6VVX0)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Lys 30 | - | expression tag |
| Thr 31 | - | expression tag |
| His 502 | - | expression tag |
| His 503 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110282.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2306.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2058.3 | |
| All* | Total formula weight | 114646.8 |
