3DL9
Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cytochrome P450 2R1 | polymer | 479 | 55141.3 | 2 | UniProt (Q6VVX0) Pfam (PF00067) In PDB | Homo sapiens | Vitamin D 25-hydroxylase |
| 2 | C, D | Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | branched | 1153.0 | 2 | In PDB BIRD (PRD_900012) GlyTouCan (G01435GL) | beta-cyclodextrin | ||
| 3 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | A, B | (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol | non-polymer | 412.6 | 2 | Chemie (V2H) | |||
| 5 | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B: 32 - 501 (UniProt: Q6VVX0)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Lys 30 | - | expression tag |
| Thr 31 | - | expression tag |
| His 502 | - | expression tag |
| His 503 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110282.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2306.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2058.3 | |
| All* | Total formula weight | 114646.8 |
