3DKJ
Crystal structure of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinamide phosphoribosyltransferase | polymer | 484 | 54805.1 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) | Homo sapiens | NAmPRTase, Nampt, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, Visfatin |
| 2 | C, E (A, B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) | |||
| 3 | D, F (A, B) | BENZAMIDE | non-polymer | 121.1 | 2 | Chemie (UNU) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109610.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1022.4 | |
| All* | Total formula weight | 110632.6 |
