3DDS
Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen phosphorylase, liver form | polymer | 848 | 97339.4 | 2 | UniProt (P06737) Pfam (PF00343) | Homo sapiens | |
| 2 | C, I (A, B) | N-acetyl-beta-D-glucopyranosylamine | non-polymer | 221.2 | 2 | Chemie (NBG) | |||
| 3 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | E, J (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 5 | F, K (A, B) | CAFFEINE | non-polymer | 194.2 | 2 | Chemie (CFF) | |||
| 6 | G, M, N (A, B) | O-tert-butyl-N-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]-L-threonine | non-polymer | 505.6 | 3 | Chemie (26B) | |||
| 7 | H (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 8 | L (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 9 | O, P (A, B) | water | water | 18.0 | 1353 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 846 (UniProt: P06737)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 194678.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3250.3 | |
| All* | Total formula weight | 197929.0 |
