3DDA
Crystal structure of the catalytic domain of Botulinum neurotoxin serotype a with a snap-25 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Botulinum neurotoxin A light chain | polymer | 430 | 49415.7 | 1 | UniProt (A5HZZ9) Pfam (PF01742) UniProt (by SIFTS) (P0DPI1) | Clostridium botulinum | Botulinum neurotoxin type A, BoNT/A, Bontoxilysin-A, BOTOX |
| 2 | B (B) | Synaptosomal-associated protein 25 | polymer | 7 | 733.9 | 1 | UniProt (P60880) | synthetic construct | SNAP-25, Synaptosomal-associated 25 kDa protein, Super protein, SUP |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence modifications
A: 1 - 424 (UniProt: A5HZZ9)
| PDB | External Database | Details |
|---|---|---|
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
| His 430 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50149.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 161.5 | |
| All* | Total formula weight | 50311.1 |
