3DD1
Crystal structure of glycogen phophorylase complexed with an anthranilimide based inhibitor GSK254
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen phosphorylase, liver form | polymer | 848 | 97339.4 | 2 | UniProt (P06737) Pfam (PF00343) | Homo sapiens | |
| 2 | C, J (A, B) | N-acetyl-beta-D-glucopyranosylamine | non-polymer | 221.2 | 2 | Chemie (NBG) PubChem (18656113) PubChem (21308223) PubChem (151446) PubChem (40549451) PubChem (40549452) PubChem (445382) PubChem (44335486) PubChem (51415028) PubChem (51415029) PubChem (53907776) PubChem (3832189) PubChem (9815885) PubChem (13422336) PubChem (101259527) PubChem (10376202) PubChem (124385630) PubChem (124799500) PubChem (124799501) PubChem (129406184) PubChem (135075397) | |||
| 3 | D, K (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) PubChem (1051) | |||
| 4 | E, L (A, B) | CAFFEINE | non-polymer | 194.2 | 2 | Chemie (CFF) PubChem (2519) | |||
| 5 | F, O (A, B) | 2-cyclohexyl-N-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]-D-alanine | non-polymer | 501.6 | 2 | Chemie (25D) PubChem (25195002) PubChem (58994882) | |||
| 6 | G, H, I, P, Q (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 7 | M, N (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) PubChem (4478249) | |||
| 8 | R, S (A, B) | water | water | 18.0 | 540 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 846 (UniProt: P06737)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 194678.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3309.7 | |
| All* | Total formula weight | 197988.4 |
