3DD1
Crystal structure of glycogen phophorylase complexed with an anthranilimide based inhibitor GSK254
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen phosphorylase, liver form | polymer | 848 | 97339.4 | 2 | UniProt (P06737) Pfam (PF00343) | Homo sapiens | |
| 2 | C, J (A, B) | N-acetyl-beta-D-glucopyranosylamine | non-polymer | 221.2 | 2 | Chemie (NBG) | |||
| 3 | D, K (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 4 | E, L (A, B) | CAFFEINE | non-polymer | 194.2 | 2 | Chemie (CFF) | |||
| 5 | F, O (A, B) | 2-cyclohexyl-N-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]-D-alanine | non-polymer | 501.6 | 2 | Chemie (25D) | |||
| 6 | G, H, I, P, Q (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 7 | M, N (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 8 | R, S (A, B) | water | water | 18.0 | 540 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 846 (UniProt: P06737)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 194678.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3309.7 | |
| All* | Total formula weight | 197988.4 |
