3DCV

Crystal structure of human Pim1 kinase complexed with 4-(4-hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1H)-one

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Proto-oncogene serine/threonine-protein kinase Pim-1	polymer	328	37596.7	1	UniProt (P11309) Pfam (PF00069)	Homo sapiens
2	B (A)	4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one	non-polymer		278.3	1	Chemie (55E)
3	C (A)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A: 2 - 313 (UniProt: P11309)

PDB	External Database	Details
Met -14	-	expression tag
Ala -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Leu -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Leu -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Pro 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37596.7
Non-Polymers*	Number of molecules	1
	Total formula weight	278.3
All*	Total formula weight	37875.0

*Water molecules are not included.