3DCR

X-ray structure of HIV-1 protease and hydrated form of ketomethylene isostere inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Chemical analogue HIV-1 protease	polymer	99	10760.6	2	Pfam (PF00077) UniProt (by SIFTS) (O38732)
2	C (B)	N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl)amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide	non-polymer		801.0	1	BIRD (PRD_001037) Chemie (KVS)
3	D, E (A, B)	water	water		18.0	113	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21521.3
Non-Polymers*	Number of molecules	1
	Total formula weight	801.0
All*	Total formula weight	22322.2

*Water molecules are not included.