3DCK
X-ray structure of D25N chemical analogue of HIV-1 protease complexed with ketomethylene isostere inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Chemical analogue HIV-1 protease | polymer | 99 | 10759.6 | 2 | Pfam (PF00077) UniProt (by SIFTS) (O38732) In PDB | ||
2 | B | (2S)-2-{[(2R,5S)-5-{[(2S,3S)-2-{[(2S,3R)-2-(acetylamino)-3-hydroxybutanoyl]amino}-3-methylpentanoyl]amino}-2-butyl-4-oxononanoyl]amino}-N~1~-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]pentanediamide | non-polymer | 783.0 | 1 | BIRD (PRD_001174) Chemie (KVI) | |||
3 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21519.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 783.0 | |
All* | Total formula weight | 22302.3 |