3DBS
Structure of PI3K gamma in complex with GDC0941
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | polymer | 960 | 109898.2 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (Human) | PI3-kinase p110 subunit gamma, PtdIns-3-kinase subunit p110, PI3K, PI3Kgamma, p120-PI3K |
| 2 | B (A) | 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | non-polymer | 513.6 | 1 | Chemie (GD9) |
Sequence modifications
A: 144 - 1102 (UniProt: P48736)
| PDB | External Database | Details |
|---|---|---|
| Met 143 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 109898.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 513.6 | |
| All* | Total formula weight | 110411.8 |
