3DAX
Crystal structure of human CYP7A1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P450 7A1 | polymer | 491 | 56469.8 | 2 | UniProt (P22680) Pfam (PF00067) | Homo sapiens (human) | Cholesterol 7-alpha-monooxygenase, CYPVII, Cholesterol 7-alpha-hydroxylase |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 4 | G, H (A, B) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 503 (UniProt: P22680)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Lys 20 | - | expression tag |
| Lys 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Ser 24 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
| His 508 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 112939.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1233.0 | |
| All* | Total formula weight | 114172.5 |
