3DAX

Crystal structure of human CYP7A1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cytochrome P450 7A1	polymer	491	56469.8	2	UniProt (P22680) Pfam (PF00067) In PDB	Homo sapiens (human)	Cholesterol 7-alpha-monooxygenase, CYPVII, Cholesterol 7-alpha-hydroxylase
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	UNKNOWN ATOM OR ION	non-polymer			2	Chemie (UNX)
4		water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 25 - 503 (UniProt: P22680)

PDB	External Database	Details
Met 18	-	expression tag
Ala 19	-	expression tag
Lys 20	-	expression tag
Lys 21	-	expression tag
Thr 22	-	expression tag
Ser 23	-	expression tag
Ser 24	-	expression tag
His 504	-	expression tag
His 505	-	expression tag
His 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112939.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1233.0
All*	Total formula weight	114172.5

*Water molecules are not included.