3D7U
Structural basis for the recognition of c-Src by its inactivator Csk
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tyrosine-protein kinase CSK | polymer | 263 | 29624.3 | 2 | UniProt (P41240) Pfam (PF07714) | Homo sapiens (Human) | C-SRC kinase, Protein-tyrosine kinase CYL |
| 2 | B, D (B, D) | Proto-oncogene tyrosine-protein kinase Src | polymer | 277 | 31801.6 | 2 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (Chicken) | pp60c-src, p60-Src, c-Src |
Sequence modifications
B, D: 260 - 523 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Lys 257 | - | expression tag |
| Asp 258 | - | expression tag |
| Ala 259 | - | expression tag |
| Glu 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Tyr 527 | - | expression tag |
| Gln 528 | - | expression tag |
| Pro 529 | - | expression tag |
| Gly 530 | - | expression tag |
| Glu 531 | - | expression tag |
| Asn 532 | - | expression tag |
| Leu 533 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 122851.7 | |
| All* | Total formula weight | 122851.7 |
