3D3H
Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Penicillin-insensitive transglycosylase | polymer | 200 | 22912.4 | 1 | UniProt (O66874) Pfam (PF00912) | Aquifex aeolicus | Peptidoglycan TGase |
| 2 | B (A) | (2R)-3-{[(S)-{[(2R,3R,4R,5S,6S)-3-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2R,3R,4S,5R,6S)-6-carbamoyl-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-6-carbamoyl-4-(carbamoyloxy)-5-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]oxy}(hydroxy)phosphoryl]oxy}-2-{[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]oxy}propanoic acid | non-polymer | 1282.1 | 1 | Chemie (M4O) | |||
| 3 | C (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 51 - 243 (UniProt: O66874)
| PDB | External Database | Details |
|---|---|---|
| Gly 44 | - | expression tag |
| Pro 45 | - | expression tag |
| Gly 46 | - | expression tag |
| Tyr 47 | - | expression tag |
| Gln 48 | - | expression tag |
| Asp 49 | - | expression tag |
| Pro 50 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22912.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 1282.1 | |
| All* | Total formula weight | 24194.6 |
