3D1N
Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3' | polymer | 14 | 4304.9 | 4 | |||
| 2 | B, D, F, H | 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3' | polymer | 14 | 4250.8 | 4 | |||
| 3 | I, J, K, L, M... | POU domain, class 6, transcription factor 1 | polymer | 151 | 17691.5 | 8 | UniProt (Q14863) Pfam (PF00157) Pfam (PF00046) In PDB | Homo sapiens (Human) | Brain-specific homeobox/POU domain protein 5,Brain-5,Brn-5,mPOU homeobox protein |
| 4 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
I, J, K, L, M, N, O, P: 142 - 292 (UniProt: Q14863)
| PDB | External Database | Details |
|---|---|---|
| Mse 144 | Leu 144 | conflict |
| Mse 172 | Leu 172 | conflict |
| Ser 186 | Cys 186 | engineered mutation |
| Mse 267 | Ile 267 | conflict |
| Ser 283 | Cys 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 175754.5 | |
| All* | Total formula weight | 175754.5 |
