3D0I

Crystal structure of spike protein receptor-binding domain from the 2005-2006 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Angiotensin-converting enzyme 2	polymer	597	69076.5	2	UniProt (Q56NL1) UniProt (Q9BYF1) Pfam (PF01401) In PDB	Paguma larvata (Masked palm civet)	ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,ACEH,Metalloprotease MPROT15
2	E, F	Spike glycoprotein	polymer	179	20391.0	2	UniProt (P59594) Pfam (PF09408) In PDB	Human SARS coronavirus (SARS-CoV)	S glycoprotein,E2,Peplomer protein
3	A, B	2-acetamido-2-deoxy-alpha-D-glucopyranose	non-polymer		221.2	5	Chemie (NDG)
4	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
7		water	water		18.0	27	Chemie (HOH)

Sequence modifications

A, B: 19 - 55 (UniProt: Q56NL1)
A, B: 56 - 615 (UniProt: Q9BYF1)
E, F: 324 - 502 (UniProt: P59594)

PDB	External Database	Details
Arg 479	Asn 479	conflict
Gly 480	Asp 480	conflict
Ser 487	Thr 487	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	178935.0
Non-Polymers*	Number of molecules	10
	Total formula weight	1529.0
All*	Total formula weight	180464.0

*Water molecules are not included.