3D0H
Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Angiotensin-converting enzyme 2 | polymer | 597 | 69076.5 | 2 | UniProt (Q56NL1) UniProt (Q9BYF1) Pfam (PF01401) In PDB | Paguma larvata (Masked palm civet) | ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,ACEH,Metalloprotease MPROT15 |
2 | E, F | Spike glycoprotein | polymer | 179 | 20421.0 | 2 | UniProt (P59594) Pfam (PF09408) In PDB | Human SARS coronavirus (SARS-CoV) | S glycoprotein,E2,Peplomer protein |
3 | A, B, F | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NDG) | |||
4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
7 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 55 (UniProt: Q56NL1)
A, B: 56 - 615 (UniProt: Q9BYF1)
E, F: 324 - 502 (UniProt: P59594)
A, B: 56 - 615 (UniProt: Q9BYF1)
E, F: 324 - 502 (UniProt: P59594)
PDB | External Database | Details |
---|---|---|
Lys 479 | Asn 479 | conflict |
Ser 487 | Thr 487 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 178995.0 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1529.0 | |
All* | Total formula weight | 180524.0 |