3D08
Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cellular tumor antigen p53 | polymer | 200 | 22454.5 | 1 | UniProt (P04637) Pfam (PF00870) In PDB | Homo sapiens (human) | Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 94 - 293 (UniProt: P04637)
PDB | External Database | Details |
---|---|---|
Arg 168 | His 168 | engineered mutation |
Ser 249 | Arg 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 22454.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 65.4 | |
All* | Total formula weight | 22519.9 |