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3CXZ

Crystal structure of cytochrome P450 CYP121 R386L mutant from M. tuberculosis

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cytochrome P450 121polymer39643261.81UniProt (P0A514)
Pfam (PF00067)
UniProt (by SIFTS) (P9WPP7)
Mycobacterium tuberculosisP450 MT2
2B, C, D
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
3E
(A)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
4F
(A)
waterwater18.0897Chemie (HOH)
Sequence modifications
A: 1 - 396 (UniProt: P0A514)
PDBExternal DatabaseDetails
Leu 386Arg 386engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43261.8
Non-Polymers*Number of molecules4
Total formula weight904.7
All*Total formula weight44166.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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