3CXH

Structure of yeast complex III with isoform-2 cytochrome c bound and definition of a minimal core interface for electron transfer.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, L (A, L)	Cytochrome b-c1 complex subunit 1, mitochondrial	polymer	431	47445.2	2	UniProt (P07256) Pfam (PF00675) Pfam (PF05193)	Saccharomyces cerevisiae (yeast)	Ubiquinol- cytochrome-c reductase complex core protein 1, Core protein I, Complex III subunit 1
2	B, M (B, M)	Cytochrome b-c1 complex subunit 2, mitochondrial	polymer	352	38751.9	2	UniProt (P07257) Pfam (PF00675)	Saccharomyces cerevisiae (yeast)	Ubiquinol- cytochrome-c reductase complex core protein 2, Core protein II, Complex III subunit 2
3	C, N (C, N)	Cytochrome b	polymer	385	43686.6	2	UniProt (P00163) Pfam (PF00033) Pfam (PF00032)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome-c reductase complex cytochrome b subunit, Cytochrome b-c1 complex subunit 3, Complex III subunit 3, Complex III subunit III, Complex III subunit CYTB, Cytochrome b-c1 complex subunit CYTB
4	D, O (D, O)	Cytochrome c1, heme protein, mitochondrial	polymer	248	27807.4	2	UniProt (P07143) Pfam (PF02167)	Saccharomyces cerevisiae (yeast)	Cytochrome c-1, Cytochrome b-c1 complex subunit 4, Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit, Complex III subunit 4, Complex III subunit IV
5	E, P (E, P)	Cytochrome b-c1 complex subunit Rieske, mitochondrial	polymer	185	20123.0	2	UniProt (P08067) Pfam (PF02921) Pfam (PF00355)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP, Complex III subunit 5
6	F, Q (F, Q)	Cytochrome b-c1 complex subunit 6	polymer	146	17144.9	2	UniProt (P00127) Pfam (PF02320)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome c reductase complex 17 kDa protein, Cytochrome c1 non-heme 17 kDa protein, Mitochondrial hinge protein, Complex III subunit 6, Complex III subunit VI
7	G, R (G, R)	Cytochrome b-c1 complex subunit 7	polymer	126	14452.6	2	UniProt (P00128) Pfam (PF02271)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome c reductase c reductase complex 14 kDa protein, Complex III subunit 7, Complex III subunit VII
8	H, S (H, S)	Cytochrome b-c1 complex subunit 8	polymer	93	10856.3	2	UniProt (P08525) Pfam (PF02939)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, Ubiquinol-cytochrome c reductase complex 11 kDa protein, Complex III subunit VII, Complex III subunit 8
9	I, T (I, T)	Cytochrome b-c1 complex subunit 9	polymer	65	7354.1	2	UniProt (P22289) Pfam (PF05365)	Saccharomyces cerevisiae (yeast)	Ubiquinol-cytochrome c reductase complex 7.3 kDa protein, Cytochrome c1 non-heme 7.3 kDa protein, Complex III subunit X, Complex III subunit 9
10	J, U (J, U)	HEAVY CHAIN (VH) OF FV-FRAGMENT	polymer	127	14365.8	2		Mus musculus (house mouse)
11	K, V (K, V)	LIGHT CHAIN (VL) OF FV-FRAGMENT	polymer	107	11926.4	2		Mus musculus (house mouse)
12	W (W)	Cytochrome c iso-2	polymer	112	12466.2	1	UniProt (P00045) Pfam (PF00034)	Saccharomyces cerevisiae (yeast)
13	X (X)	beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900003)		sucrose
14	KA, Y (L, A)	UNDECYL-MALTOSIDE	non-polymer		496.6	2	Chemie (UMQ)
15	AA, FA, MA, NA, RA... (C, D, N, O, W)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	7	Chemie (HEM)
16	BA, OA (C, N)	STIGMATELLIN A	non-polymer		514.6	2	Chemie (SMA)
17	CA, PA (C, N)	(2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate	non-polymer		692.0	2	Chemie (8PE)
18	DA, QA (C, N)	(2R,5R,11S,14R)-2-(butanoyloxy)-5,8,11-trihydroxy-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate	non-polymer		764.7	2	Chemie (CN6)
19	EA, LA (C, N)	(1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate	non-polymer		593.8	2	Chemie (9PE)
20	GA, SA (D, O)	(1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate	non-polymer		564.7	2	Chemie (7PH)
21	HA, TA (E, P)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
22	IA, JA (E, L)	(1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate	non-polymer		592.8	2	Chemie (6PH)
23	AB, BB, CB, DB, EB... (F, G, H, I, J...)	water	water		18.0	548	Chemie (HOH)

Sequence modifications

A, L: 27 - 457 (UniProt: P07256)

PDB	External Database	Details
Asp 153	Glu 153	conflict

Contents of the asymmetric unit

Polymers	Number of chains	23
	Total formula weight	520294.6
Branched	Number of molecules	1
	Total formula weight	342.3
Non-Polymers*	Number of molecules	23
	Total formula weight	13105.5
All*	Total formula weight	533742.3

*Water molecules are not included.