3CWK
Crystal Structure of the R132K:Y134F:R111L:T54V:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-trans-Retinoic Acid at 1.57 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15507.7 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinoic acid-binding protein II, CRABP-II, Retinoic acid-binding protein II, cellular |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | RETINOIC ACID | non-polymer | 300.4 | 1 | Chemie (REA) PubChem (5538) PubChem (23275881) PubChem (25145416) PubChem (444795) PubChem (449171) PubChem (5282379) PubChem (6336207) PubChem (6336229) PubChem (6419708) PubChem (87179195) PubChem (87519764) PubChem (87980058) PubChem (88439848) PubChem (88525859) PubChem (88604688) PubChem (6603983) PubChem (9796370) PubChem (9861147) PubChem (445925) PubChem (10881132) PubChem (12358677) PubChem (12358678) PubChem (12358679) PubChem (12358681) PubChem (134688661) PubChem (139597075) PubChem (145826768) PubChem (166478803) | |||
| 4 | D (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Val 54 | Thr 55 | engineered mutation |
| Leu 111 | Arg 112 | engineered mutation |
| Glu 121 | Leu 122 | engineered mutation |
| Lys 132 | Arg 133 | engineered mutation |
| Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15507.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 396.5 | |
| All* | Total formula weight | 15904.2 |
