3CWK
Crystal Structure of the R132K:Y134F:R111L:T54V:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-trans-Retinoic Acid at 1.57 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15507.7 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinoic acid-binding protein II, CRABP-II, Retinoic acid-binding protein II, cellular |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | RETINOIC ACID | non-polymer | 300.4 | 1 | Chemie (REA) | |||
| 4 | D (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Val 54 | Thr 55 | engineered mutation |
| Leu 111 | Arg 112 | engineered mutation |
| Glu 121 | Leu 122 | engineered mutation |
| Lys 132 | Arg 133 | engineered mutation |
| Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15507.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 396.5 | |
| All* | Total formula weight | 15904.2 |
