3CUP
Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | H-2 class II histocompatibility antigen, A-D alpha chain | polymer | 190 | 21623.1 | 1 | UniProt (P04228) Pfam (PF00993) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
2 | B | MHC class II H2-IA-beta chain linked to GAD221-235 peptide | polymer | 222 | 25539.5 | 1 | UniProt (Q6LDA5) UniProt (Q31135) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (Q05683) In PDB | Mus musculus (mouse) | |
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) |
Sequence modifications
A: -2 - 178 (UniProt: P04228)
B: 221 - 235 (UniProt: Q6LDA5)
B: null - 428 (UniProt: Q31135)
PDB | External Database | Details |
---|---|---|
Ser 179 | - | expression tag |
Ser 180 | - | expression tag |
Ala 181 | - | expression tag |
Asp 182 | - | expression tag |
Leu 183 | - | expression tag |
Val 184 | - | expression tag |
Pro 185 | - | expression tag |
Arg 186 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 215 | - | expression tag |
Ser 216 | - | expression tag |
His 217 | - | expression tag |
Ser 218 | - | expression tag |
Arg 219 | - | expression tag |
Gly 220 | - | expression tag |
Gly 236 | - | linker |
Ser | - | linker |
Gly | - | linker |
Ser | - | linker |
Gly | - | linker |
Ser | - | linker |
PDB | External Database | Details |
---|---|---|
Ser 429 | - | expression tag |
Ser 430 | - | expression tag |
Ala 431 | - | expression tag |
Asp 432 | - | expression tag |
Leu 433 | - | expression tag |
Val 434 | - | expression tag |
Pro 435 | - | expression tag |
Arg 436 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47162.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 459.5 | |
All* | Total formula weight | 47622.1 |