3CU1
Crystal Structure of 2:2:2 FGFR2D2:FGF1:SOS complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Fibroblast growth factor receptor 2 | polymer | 100 | 11608.3 | 2 | UniProt (P21802) Pfam (PF07679) In PDB | Homo sapiens (Human) | FGFR-2, Keratinocyte growth factor receptor 2, CD332 antigen |
| 2 | B, D | Heparin-binding growth factor 1 | polymer | 131 | 14942.9 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (Human) | HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF- beta |
| 3 | E, F | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | branched | 982.8 | 2 | In PDB BIRD (PRD_900013) | sucrose octasulfate | ||
| 4 | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53102.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1965.6 | |
| All* | Total formula weight | 55067.9 |
