3COK
Crystal structure of PLK4 kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK4 | polymer | 278 | 31723.7 | 2 | UniProt (O00444) Pfam (PF00069) | Homo sapiens (human) | Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase Sak, Serine/threonine-protein kinase 18 |
| 2 | C, D, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | E, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 274 (UniProt: O00444)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Glu 275 | - | expression tag |
| Gly 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63447.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1396.6 | |
| All* | Total formula weight | 64844.0 |
