3CKX

Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein kinase 24	polymer	304	34653.2	1	UniProt (Q9Y6E0) Pfam (PF00069)	Homo sapiens (human)	STE20-like kinase MST3, MST-3, Mammalian STE20-like protein kinase 3
2	B (A)	STAUROSPORINE	non-polymer		466.5	1	Chemie (STU)
3	C (A)	water	water		18.0	26	Chemie (HOH)

Sequence modifications

A: 4 - 296 (UniProt: Q9Y6E0)

PDB	External Database	Details
Met 1	-	expression tag
Ser 2	-	expression tag
Leu 3	-	expression tag
Glu 297	-	expression tag
Gly 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34653.2
Non-Polymers*	Number of molecules	1
	Total formula weight	466.5
All*	Total formula weight	35119.7

*Water molecules are not included.