3CIC
Structure of BACE Bound to SCH709583
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Beta-secretase 1 | polymer | 390 | 43426.0 | 2 | UniProt (P56817) Pfam (PF00026) In PDB | Homo sapiens (human) | Beta-site APP cleaving enzyme 1; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2; Memapsin-2; Aspartyl protease 2; Asp 2; ASP2 |
| 2 | A, B | N'-[(1S,2S)-2-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | non-polymer | 620.7 | 2 | Chemie (316) | |||
| 3 | A, B | D(-)-TARTARIC ACID | non-polymer | 150.1 | 2 | Chemie (TAR) | |||
| 4 | water | water | 18.0 | 969 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86851.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1541.6 | |
| All* | Total formula weight | 88393.6 |
