3CBZ
The Dvl2 PDZ Domain in Complex with the N2 Inhibitory Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dishevelled-2 | polymer | 108 | 11424.9 | 1 | UniProt (O14641) Pfam (PF00595) | Homo sapiens (Human) | Segment polarity protein dishevelled homolog DVL-2, DSH homolog 2 |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 264 - 354 (UniProt: O14641)
| PDB | External Database | Details |
|---|---|---|
| Gly 260 | - | expression tag |
| Ser 261 | - | expression tag |
| His 262 | - | expression tag |
| Met 263 | - | expression tag |
| Ser 354 | Cys 354 | engineered mutation |
| Gly 355 | - | linker |
| Gly 356 | - | linker |
| Gly 357 | - | linker |
| Ser 358 | - | SEE REMARK 999 |
| Gly 359 | - | SEE REMARK 999 |
| Asn 360 | - | SEE REMARK 999 |
| Glu 361 | - | SEE REMARK 999 |
| Val 362 | - | SEE REMARK 999 |
| Trp 363 | - | SEE REMARK 999 |
| Ile 364 | - | SEE REMARK 999 |
| Asp 365 | - | SEE REMARK 999 |
| Gly 366 | - | SEE REMARK 999 |
| Pro 367 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11424.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 219.1 | |
| All* | Total formula weight | 11644.0 |
