3CBQ
Crystal structure of the human REM2 GTPase with bound GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding protein REM 2 | polymer | 195 | 21981.7 | 1 | UniProt (Q8IYK8) Pfam (PF00071) | Homo sapiens (human) | Rad and Gem-like GTP-binding protein 2 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | F (A) | UNKNOWN ATOM OR ION | non-polymer | 1 | Chemie (UNX) | ||||
| 6 | G (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 110 - 286 (UniProt: Q8IYK8)
| PDB | External Database | Details |
|---|---|---|
| Met 92 | - | expression tag |
| His 93 | - | expression tag |
| His 94 | - | expression tag |
| His 95 | - | expression tag |
| His 96 | - | expression tag |
| His 97 | - | expression tag |
| His 98 | - | expression tag |
| Ser 99 | - | expression tag |
| Ser 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Arg 102 | - | expression tag |
| Glu 103 | - | expression tag |
| Asn 104 | - | expression tag |
| Leu 105 | - | expression tag |
| Tyr 106 | - | expression tag |
| Phe 107 | - | expression tag |
| Gln 108 | - | expression tag |
| Gly 109 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21981.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 591.6 | |
| All* | Total formula weight | 22573.3 |
