3CBQ

Crystal structure of the human REM2 GTPase with bound GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GTP-binding protein REM 2	polymer	195	21981.7	1	UniProt (Q8IYK8) Pfam (PF00071)	Homo sapiens (human)	Rad and Gem-like GTP-binding protein 2
2	B (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	C (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
4	D, E (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	F (A)	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
6	G (A)	water	water		18.0	70	Chemie (HOH)

Sequence modifications

A: 110 - 286 (UniProt: Q8IYK8)

PDB	External Database	Details
Met 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
Ser 99	-	expression tag
Ser 100	-	expression tag
Gly 101	-	expression tag
Arg 102	-	expression tag
Glu 103	-	expression tag
Asn 104	-	expression tag
Leu 105	-	expression tag
Tyr 106	-	expression tag
Phe 107	-	expression tag
Gln 108	-	expression tag
Gly 109	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21981.7
Non-Polymers*	Number of molecules	5
	Total formula weight	591.6
All*	Total formula weight	22573.3

*Water molecules are not included.