3CAQ
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADPH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | 3-oxo-5-beta-steroid 4-dehydrogenase | polymer | 326 | 37427.9 | 2 | UniProt (P51857) Pfam (PF00248) | Homo sapiens (human) | Delta(4)-3-ketosteroid 5-beta-reductase, Aldo-keto reductase family 1 member D1 |
2 | C, H (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | D, I (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
4 | E, F, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | G, K (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
6 | L, M (A, B) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 74855.8 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2069.7 | |
All* | Total formula weight | 76925.5 |