3C6L
Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | TCR 2W20 alpha chain | polymer | 185 | 20957.3 | 2 | Pfam (PF09291) UniProt (by SIFTS) (P01849) | Mus musculus (house mouse) | |
| 2 | B, F (B, F) | TCR 2W20 beta chain | polymer | 236 | 26487.3 | 2 | Pfam (PF07654) UniProt (by SIFTS) (P01852) | Mus musculus (house mouse) | |
| 3 | C, G (C, G) | H-2 class II histocompatibility antigen, A-B alpha chain | polymer | 182 | 20598.0 | 2 | UniProt (P14434) Pfam (PF00993) Pfam (PF07654) | Mus musculus (house mouse) | IAalpha |
| 4 | D, H (D, H) | 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain) | polymer | 217 | 24938.8 | 2 | UniProt (P14483) Pfam (PF00969) Pfam (PF07654) | Mus musculus (house mouse) | |
| 5 | I, J, K (A, E) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) |
Sequence modifications
D, H: 29 - 217 (UniProt: P14483)
D, H: 1 - 13 (PDB: 3C6L)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | linker |
| Gly 15 | - | linker |
| Gly 16 | - | linker |
| Gly 17 | - | linker |
| Ser 18 | - | linker |
| Leu 19 | - | linker |
| Val 20 | - | linker |
| Pro 21 | - | linker |
| Arg 22 | - | linker |
| Gly 23 | - | linker |
| Ser 24 | - | linker |
| Gly 25 | - | linker |
| Gly 26 | - | linker |
| Gly 27 | - | linker |
| Gly 28 | - | linker |
| Lys 216 | Arg 217 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 185962.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 120.2 | |
| All* | Total formula weight | 186083.0 |
