3C6E

Crystal structure of the precursor membrane protein- envelope protein heterodimer from the dengue 2 virus at neutral pH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Envelope protein E	polymer	402	44801.4	1	UniProt (O09234) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (O11875) In PDB	Dengue virus 2 Thailand/16681/84
2	C	prM	polymer	130	14870.9	1	UniProt (O09234) Pfam (PF01570) Pfam (PF01004) UniProt (by SIFTS) (Q3BCY3) In PDB	Dengue virus
3	B	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G49078BH)
4	C	2-acetamido-2-deoxy-alpha-D-glucopyranose	non-polymer		221.2	1	Chemie (NDG)
5	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6		water	water		18.0	45	Chemie (HOH)

Sequence modifications

A: 1 - 394 (UniProt: O09234)

PDB	External Database	Details
Gly -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

C: 1 - 130 (UniProt: O09234)

PDB	External Database	Details
Ser 87	Arg 201	engineered mutation
Thr 88	Arg 202	engineered mutation
Ser 91	Arg 205	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59672.3
Branched	Number of molecules	1
	Total formula weight	748.7
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	60863.4

*Water molecules are not included.