3C50

Crystal Structure of G protein coupled receptor kinase 1 bound to ADP and magnesium chloride at 2.6A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Rhodopsin kinase	polymer	543	61429.9	2	UniProt (P28327) Pfam (PF00615) Pfam (PF00069)	Bos taurus (cattle)	RK, G protein-coupled receptor kinase 1
2	C, D, K, L (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	E, F, G, J, M... (A, B)	CHLORIDE ION	non-polymer		35.5	8	Chemie (CL)
4	H, Q (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
5	I (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
6	R, S (A, B)	water	water		18.0	303	Chemie (HOH)

Sequence modifications

A, B: 1 - 535 (UniProt: P28327)

PDB	External Database	Details
Val 536	-	expression tag
Asp 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122859.9
Non-Polymers*	Number of molecules	15
	Total formula weight	1430.5
All*	Total formula weight	124290.4

*Water molecules are not included.