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3C31

Crystal structure of GluR5 ligand-binding core in complex with lithium at 1.49 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1polymer25829253.62UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Rat)Glutamate receptor 5, GluR-5, GluR5
2C, K
(A, B)
LITHIUM IONnon-polymer6.92Chemie (LI)
3D, E, F, L
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4G, N
(A, B)
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.22Chemie (KAI)
5H, I, J, O
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
6M
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
7P, Q
(A, B)
waterwater18.0690Chemie (HOH)
Sequence modifications
A, B: 3 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
A, B: 119 - 258 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58507.1
Non-Polymers*Number of molecules13
Total formula weight1046.6
All*Total formula weight59553.7
*Water molecules are not included.

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PDB entries from 2025-07-30

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