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3C31

Crystal structure of GluR5 ligand-binding core in complex with lithium at 1.49 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1polymer25829253.62UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Rat)Glutamate receptor 5, GluR-5, GluR5
2C, K
(A, B)
LITHIUM IONnon-polymer6.92Chemie (LI)
PubChem (28486)
3D, E, F, L
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
PubChem (312)
4G, N
(A, B)
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.22Chemie (KAI)
PubChem (3816)
PubChem (10255)
PubChem (73345)
PubChem (3083828)
PubChem (5317452)
PubChem (5318769)
PubChem (6453379)
PubChem (6604705)
PubChem (10036135)
PubChem (11095940)
PubChem (23616889)
PubChem (45039619)
PubChem (6603893)
PubChem (101994997)
PubChem (135037246)
5H, I, J, O
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
PubChem (753)
6M
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
7P, Q
(A, B)
waterwater18.0690Chemie (HOH)
Sequence modifications
A, B: 3 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
A, B: 119 - 258 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58507.1
Non-Polymers*Number of molecules13
Total formula weight1046.6
All*Total formula weight59553.7
*Water molecules are not included.

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PDB entries from 2026-04-08

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