3C22

Crystal structure of the carbohydrate recognition domain of human Langerin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	C-type lectin domain family 4 member K	polymer	156	17949.0	4	UniProt (Q9UJ71) Pfam (PF00059) In PDB	Homo sapiens (Human)	Langerin, CD207 antigen
2	A, B, C, D	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4		water	water		18.0	873	Chemie (HOH)

Sequence modifications

A, B, C, D: 188 - 328 (UniProt: Q9UJ71)

PDB	External Database	Details
Ala 173	-	EXPRESSION TAG
Ser 174	-	EXPRESSION TAG
Trp 175	-	EXPRESSION TAG
Ser 176	-	EXPRESSION TAG
His 177	-	EXPRESSION TAG
Pro 178	-	EXPRESSION TAG
Gln 179	-	EXPRESSION TAG
Phe 180	-	EXPRESSION TAG
Glu 181	-	EXPRESSION TAG
Lys 182	-	EXPRESSION TAG
Ile 183	-	EXPRESSION TAG
Glu 184	-	EXPRESSION TAG
Gly 185	-	EXPRESSION TAG
Arg 186	-	EXPRESSION TAG
Met 187	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71796.1
Non-Polymers*	Number of molecules	10
	Total formula weight	306.1
All*	Total formula weight	72102.3

*Water molecules are not included.