3C11

Yeast Hsp82 N-terminal domain-Geldanamycin complex: effects of mutants 98-99 KS-AA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ATP-dependent molecular chaperone HSP82	polymer	240	26970.7	1	UniProt (P02829) Pfam (PF02518)	Saccharomyces cerevisiae (Baker's yeast)	Heat shock protein Hsp90 heat-inducible isoform, 82 kDa heat shock protein
2	B (A)	GELDANAMYCIN	non-polymer		560.6	1	Chemie (GDM)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E (A)	water	water		18.0	297	Chemie (HOH)

Sequence modifications

A: 1 - 220 (UniProt: P02829)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ala 98	Lys 98	engineered mutation
Ala 99	Ser 99	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26970.7
Non-Polymers*	Number of molecules	3
	Total formula weight	744.8
All*	Total formula weight	27715.5

*Water molecules are not included.