3BZ3
Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Focal adhesion kinase 1 | polymer | 276 | 31757.7 | 1 | UniProt (Q05397) Pfam (PF07714) In PDB | Homo sapiens (human) | FADK 1, pp125FAK, Protein-tyrosine kinase 2 |
2 | A | N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | non-polymer | 507.5 | 1 | Chemie (YAM) | |||
3 | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31757.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 507.5 | |
All* | Total formula weight | 32265.2 |