3BYS

co-crystal structure of Lck and aminopyrimidine amide 10b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proto-oncogene tyrosine-protein kinase LCK	polymer	277	32057.7	1	UniProt (P06239) Pfam (PF07714) In PDB	Homo sapiens (Human)	p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell-specific protein-tyrosine kinase
2	A	4-methyl-N~3~-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)-N~1~-[3-(trifluoromethyl)phenyl]benzene-1,3-dicarboxamide	non-polymer		589.6	1	Chemie (AM5)
3		water	water		18.0	51	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32057.7
Non-Polymers*	Number of molecules	1
	Total formula weight	589.6
All*	Total formula weight	32647.3

*Water molecules are not included.