3BYS
co-crystal structure of Lck and aminopyrimidine amide 10b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase LCK | polymer | 277 | 32057.7 | 1 | UniProt (P06239) Pfam (PF07714) | Homo sapiens (Human) | p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell-specific protein-tyrosine kinase |
| 2 | B (A) | 4-methyl-N~3~-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)-N~1~-[3-(trifluoromethyl)phenyl]benzene-1,3-dicarboxamide | non-polymer | 589.6 | 1 | Chemie (AM5) | |||
| 3 | C (A) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32057.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 589.6 | |
| All* | Total formula weight | 32647.3 |
