3BYO
X-Ray co-crystal structure of 2-amino-6-phenylpyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one 25 bound to Lck
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase LCK | polymer | 271 | 31425.9 | 1 | UniProt (P06239) Pfam (PF07714) | Homo sapiens (human) | p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell-specific protein-tyrosine kinase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | 6-(2,6-dimethylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | non-polymer | 530.6 | 1 | Chemie (AM9) | |||
| 4 | D (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31425.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 626.7 | |
| All* | Total formula weight | 32052.6 |
