3BVJ

Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with XMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Uridine 5'-monophosphate synthase	polymer	312	34054.2	2	UniProt (P11172) Pfam (PF00215) In PDB	Homo sapiens (Human)	UMP synthase, Orotidine 5'-phosphate decarboxylase, OMPdecase
2	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A, B	XANTHOSINE-5'-MONOPHOSPHATE	non-polymer		365.2	2	Chemie (XMP)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	311	Chemie (HOH)

Sequence modifications

A, B: 1 - 291 (UniProt: P11172)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68108.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1014.6
All*	Total formula weight	69123.0

*Water molecules are not included.