3BUC
X-ray structure of human ABH2 bound to dsDNA with Mn(II) and 2KG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3') | polymer | 13 | 3981.6 | 1 | |||
2 | C | DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DGP*DTP*DTP*DAP*DTP*DAP*DCP*DA)-3') | polymer | 13 | 3950.6 | 1 | |||
3 | A | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 203 | 23136.4 | 1 | UniProt (Q6NS38) Pfam (PF13532) In PDB | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, Oxy DC1 |
4 | B | propane-1-thiol | non-polymer | 76.2 | 1 | Chemie (XL3) | |||
5 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
6 | A | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
7 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: 56 - 258 (UniProt: Q6NS38)
PDB | External Database | Details |
---|---|---|
Ser 67 | Cys 67 | engineered mutation |
Ser 165 | Cys 165 | engineered mutation |
Cys 169 | Gly 169 | engineered mutation |
Ser 192 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 31068.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 277.2 | |
All* | Total formula weight | 31345.8 |