3BU3
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | insulin receptor subunit beta | polymer | 306 | 35033.7 | 1 | UniProt (P06213) Pfam (PF07714) | Homo sapiens (human) | IR, CD220 antigen |
| 2 | B (B) | Insulin receptor substrate 2 | polymer | 15 | 1715.8 | 1 | UniProt (P81122) | IRS-2, 4PS | |
| 3 | C, D (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 978 - 1283 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| Ser 981 | Cys 1008 | engineered mutation |
| Asn 1251 | Lys 1278 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36749.4 | |
| All* | Total formula weight | 36749.4 |
