3BTZ
Crystal structure of human ABH2 cross-linked to dsDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 202 | 22977.3 | 1 | UniProt (Q6NS38) Pfam (PF13532) In PDB | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, Oxy DC1 |
| 2 | B | DNA (5'-D(*AP*GP*GP*TP*GP*AP*(2YR)P*AP*AP*TP*GP*CP*G)-3') | polymer | 13 | 4100.8 | 1 | |||
| 3 | C | DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DTP*DTP*DAP*DTP*DCP*DAP*DCP*DC)-3') | polymer | 13 | 3886.5 | 1 | |||
| 4 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 57 - 258 (UniProt: Q6NS38)
| PDB | External Database | Details |
|---|---|---|
| Ser 67 | Cys 67 | engineered mutation |
| Ser 165 | Cys 165 | engineered mutation |
| Cys 175 | Glu 175 | engineered mutation |
| Ser 192 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30964.6 | |
| All* | Total formula weight | 30964.6 |
