3BRV

NEMO/IKKb association domain structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Inhibitor of nuclear factor kappa-B kinase subunit beta	polymer	48	5437.0	2	UniProt (O14920) Pfam (PF12179) In PDB		I-kappa-B-kinase beta, IkBKB, IKK-beta, IKK-B, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB
2	B, D	NF-kappa-B essential modulator	polymer	70	8533.7	2	UniProt (Q9Y6K9) Pfam (PF11577) In PDB	Homo sapiens (human)	NEMO, NF-kappa-B essential modifier, Inhibitor of nuclear factor kappa-B kinase subunit gamma, IkB kinase subunit gamma, I-kappa-B kinase gamma, IKK-gamma, IKKG, IkB kinase-associated protein 1, IKKAP1, FIP-3
3		water	water		18.0	103	Chemie (HOH)

Sequence modifications

A, C: 701 - 745 (UniProt: O14920)

PDB	External Database	Details
Ala 698	-	expression tag
Met 699	-	expression tag
Ala 700	-	expression tag

B, D: 44 - 111 (UniProt: Q9Y6K9)

PDB	External Database	Details
Met 42	-	expression tag
Trp 43	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	27941.4
All*	Total formula weight	27941.4

*Water molecules are not included.