3BQR
Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an imidazo-pyridazine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Death-associated protein kinase 3 | polymer | 283 | 32545.1 | 1 | UniProt (O43293) Pfam (PF00069) | Homo sapiens (human) | DAP kinase 3, DAP-like kinase, Dlk, ZIP-kinase |
| 2 | B (A) | 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid | non-polymer | 326.4 | 1 | Chemie (4RB) | |||
| 3 | C, D (A) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 2 | Chemie (PGO) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 9 - 289 (UniProt: O43293)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | - | expression tag |
| Met 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32545.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 570.6 | |
| All* | Total formula weight | 33115.8 |
